81377 München christian.haass(at)dzne.de +49 89 4400-46549 Areas of investigation/research focus Professor. Haass started to work on Alzheimer's disease (AD) hinein 1990 at a time, when very little was known about the cellular mechanisms involved. Based on the pathology, which shows invariably the accumulation and deposition of Amyloid ß-peptide (Aß), he focused his work on the generation and metabolism of Aß. Christian Haass hypothesized against the widely accepted general opinion rein this field that Aß may Beryllium produced from its precursor rein a physiologically normal pathway and not necessarily hinein a pathological process. Indeed he found by using very simple tissue culture systems that Aß is produced and liberated under physiological conditions. This pivotal finding welches a major breakthrough for the entire field, since it allowed elucidating the molecular principles behind Aß generation as well as the identification of the enzymes (the so-called secretases) involved in generation and liberation of the peptide and finally the development of selective inhibitors to therapeutically lower Aß production in patients.
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Together with an interdiziplinary Mannschaft he uncovered the molecular mechanisms of Alzheimer's disease and identified target molecules for therapeutic treatment.
Der markante Hütte mit den drei hohen Türmen wurde aus massiven Sandsteinblöcken erbaut zumal besitzt eine dekorative Rosette ansonsten ein Giebeldach.
Christian Haass, Professor of Metabolic Biochemistry at LMU Munich and spokesperson for the DZNE Munich, is known for his groundbreaking research in Alzheimer's disease. His Mehr Info work focuses on the molecular and cellular mechanisms of this disease hinein order to gain fundamental insights into its development.
Gut: Ich habe leider nicht an meine Termin erscheinen außerdem nehme ich komplett Verantwortung aber habe ich erwartet das nach minderst die Hälfte oder eine Gutschein erwartet leider habe ich meine Nachtgebet Währungs verloren.
Christian Haass is a German Biochemist and known for his work on the cell biology of neurodegenerative diseases.
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